SSC Subcommittee on Hemostasis and Thrombosis in Liver Disease

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This subcommittee is focused on supporting awareness of and research into the complex hemostatic changes in patients with liver diseases and the associated bleeding or thrombotic complications. It incorporates internists, hematologists, hepatologists, laboratory scientists and is addressed to a large spectrum of specialists.

If you are interested in the subcommittee and want to follow its activity, please click the "join community" button.

Mandate

  • To better understand how to prevent or treat bleeding and thrombosis in patients with liver diseases.
  • To continue and expand on educational activities specifically aimed at communicating important changes in clinical management of patients, including approaches to thromboprophylaxis.
  • To generate guidance documents, provide ISTH-supported educational programs and initiate ISTH-led international registries associated with hemostatic management of patients with liver diseases.

Leadership:

  • Chair - Lara Roberts
  • Co-chair - Tushar Sehgal
  • Co-chair - Stephanie Carlin
  • Co-chair - Alex Gatt
  • Co-chair - Virginia Hernandez-Gea
  • Co-chair - James Luyendyk
  • Co-chair - Ton Lisman 
  • Co-chair - Simon Stanworth
  • Co-chair - Amber Afzal

Completed Projects

Thromboprophylaxis for venous thromboembolism prevention in hospitalized patients with cirrhosis: Guidance from the SSC of the ISTH project completed; published October 2022

Periprocedural management of abnormal coagulation parameters and thrombocytopenia in patients with cirrhosis: Guidance from the SSC of the ISTH project completed; published January 2022

The concept of rebalanced hemostasis in patients with liver disease: Communication from the ISTH SSC working group on hemostatic management of patients with liver disease project completed; published April 2021

Official Communications:

Latest Discussions

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Announcements

  • Your participation in an anticoagulation practices for adults survey is being requested!

    Invitation to Participate in an ISTH Survey:

    Dear ISTH member, you are invited to participate in a brief survey on anticoagulation practices for adults with cirrhosis and systemic venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE).

    The purpose of this survey is to better understand clinician perspectives and real-world practice patterns in managing anticoagulation for this vulnerable population. Your responses will help identify areas of consensus and practice variation, informing future research and clinical guidance.

    What to expect

    • One-time anonymous survey
    • Approximately 10 minutes to complete
    • No identifying information will be collected
    • Participation is completely voluntary

    Take the survey here:

    https://redcap.isth.org/surveys/?s=NX4AL8FXE8TNT89N

    This study is being conducted by the ISTH SSC on Thrombosis and Hemostasis in Liver Disease (SSC Subcommittee on Hemostasis and Thrombosis in Liver Disease - ISTH Community) in collaboration with the investigators at the Washington University School of Medicine in St. Louis, USA.

    If you have any questions, please contact Amir Mahmoud, MBBCh at amirm@wustl.edu.

    Thank you for considering participation. Your expertise will help improve the care of patients with cirrhosis and VTE.

  • Your participation in the PATRIC Study is being requested!

    Greetings, esteemed clinicians and scientists.

    Your participation in the PATRIC (Practice of TRansfusion in Cirrhosis) study is being requested: kindly see the accompanying graphic for further information on how to participate in the study, as well as contact information for the principal investigators involved.

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University Medical Center Groningen UMCG
Netherlands