SSC Subcommittee on Cancer-Associated Thrombosis & Hemostasis

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This Subcommittee is focused on the spectrum of clinical disorders of hemostasis in malignancy, including venous and arterial thromboembolism, and bleeding. The Subcommittee comprises of members from diverse backgrounds and disciplines including hematologists, oncologists, surgeons, pulmonologists, epidemiologists, and translational and basic scientists.

If you are interested in the subcommittee and want to follow its activity, please click "join community" to participate.

Mandate

  • Environment: To create an atmosphere and culture of collaboration between investigators and clinicians from different disciplines and backgrounds, leading to a focus on priority areas related to the field of thrombosis and hemostasis in malignancy
  • Research: To develop, organize and execute collaborative studies through interdisciplinary collaboration and prioritization including clinical and laboratory standards and methods
  • Education: To educate members of the ISTH and the broader medical community on issues of clinical significance, with an emphasis on patient-centered outcomes
  • Guidance: To examine existing data, identify areas of unmet need and provide clinical guidance to the medical community
  • Dissemination: To develop, publish and disseminate reports that result from the activities listed above

If you are a member of the Society and would like to know how to participate in the work of this group, please join the group to receive updates on activity or submit an Expression of Interest Form to the Chairman or any of the Co-Chairmen. We would be pleased to learn of your interest.

Leadership

  • Chair - Kristen Sanfilippo
  • Co-chair - Aurélien Delluc
  • Co-chair - Avi Leader
  • Co-chair - Nick van Es 
  • Co-chair - Mandy Lauw 
  • Co-chair - Rushad Patell
  • Co-chair - Florian Moik
  • Co-chair - Karlyn Martin
  • Co-chair - Darko Antic

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Announcements

  • We invite your institution to participate in a multicenter retrospective cohort study: PAUSE CAT

    We are writing to invite your institution to participate in a multicenter retrospective cohort study titled:

    "PAUSE CAT" [Perioperative Anticoagulation Use and Suspension Evaluation in Cancer-Associated Thrombosis]

    This collaborative project aims to better understand thrombotic and bleeding outcomes in patients with newly diagnosed cancer-associated thrombosis undergoing procedures requiring temporary anticoagulation interruption.

    Study Highlights:

    Design: Retrospective chart review via EMR
    Inclusion: Adults with active malignancy and new VTE undergoing a procedure within 30 days of VTE diagnosis
    Outcomes: Recurrent VTE, embolic events, bleeding complications, and mortality within 6 months
    Data Collection: Standardized REDCap form
    Site Requirements: Local IRB approval and data use agreement

    This study represents a valuable opportunity to advance our understanding of real-world anticoagulation complications in high-risk oncology populations, and we hope to include a diverse cohort of institutions.

    If your team is interested in participating or would like more information, please don’t hesitate to reach out. We would be happy to set up a meeting to discuss logistics and next steps.

    Avi Leader

    Memorial Sloan Kettering Cancer Center

    leadera@mskcc.org

    Rushad Patell

    Beth Israel Deaconess Medical

    Centerrpatell@bidmc.harvard.edu

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Washington University St. Louis
United States