SSC Subcommittee on Pediatric and Neonatal Thrombosis and Hemostasis

The Subcommittee is focused on addressing clinical and scientific issues in pediatric (including neonatal) thrombosis and hemostasis.

If you are interested in the subcommittee and want to follow its activity, please click "join community" to participate.

Mandate

• To address issues in area of thrombosis in children and neonates.
• To address issues in area of hemostasis in children and neonates.
• To develop clinical standards for evaluation of children and neonates suffering from hemostasis and thrombosis problems.
• To develop clinical research standards recommendations in children and neonates with hemostatic and thrombotic issues.
• To develop international collaboration using registries, cooperative cohort studies, clinical trials or other appropriate methods in rare hemostasis and thrombosis problems in children and neonates.
• To generate, publish and distribute reports and recommendations relating to pediatric and neonatal laboratory methods, standards and patient care.
• To collaborate with other SSCs in appropriate situations.
• To engage diverse, international, inter-disciplinary, inter-professional participation and representation at all stages of career, in all Pediatric/Neonatal SSC activities and initiatives.

Role

The following are the ongoing activities and responsibilities of the Subcommittee.

• Educational Program: To continue to provide latest updates to all stakeholder communities (specialists, primary care providers, patients/parents, etc.) on diagnosis, treatment, outcomes, and prevention of disorders pediatric thrombosis and hemostasis, as well as latest recommendations, standards, guidelines/guidances, and research opportunities. 
• Joint SSC Work: To continue to collaborate with other SSC chairs to promote crossover work, including for example physiologic inhibitors and thrombophilia, control of anticoagulation, and women’s health.
• Position Papers: To continue to generate position papers to define current status in pediatric thrombosis & hemostasis and related research as well as to generate clinical guidance papers.
• Working Parties: Groups of experts (hematologists and non-hematologists) have been assembled to further develop position papers relating to a variety of pediatric thrombosis & hemostasis issues.
• Cooperative Registry and Cohort Study Initiation and Support: Promoting international collaboration to develop/maintain registries and cohort studies for rare pediatric thrombosis and hemostasis issues. Recent examples include the IPTN, AT registry, and severe PC registry.

If you are a member of the Society and would like to know how to participate in the work of this group, please join the group to receive updates on activity or submit an Expression of Interest Form to the Chairman or any of the Co-Chairmen. We would be pleased to learn of your interest.

Leadership

• Chair - Neil Goldenberg
• Co-chair - Assaf Barg
• Co-chair - Vince Faustino
• Co-chair - Madhvi Rajpurkar
• Co-chair - Mattia Rizzi
• Co-chair - Nongnuch Sirachainan
• Co-chair - Lakshmi Srivaths
• Co-chair - Hilary Whitworth 

Working Parties

• Pulmonary Embolism (Lead: Madhvi Rajpurkar)
• Catheter associated NeoVTE (CA-NeoVTE) (Lead: Dr. Rukhmi Bhat, Dr. C H Heleen van Ommen)
• Hemostasis (Lead: Nongnuch Sirachainan)
• Antithrombotic Trials (Co-Leads: Neil Goldenberg & Christoph Male)
• Medication Adherence (Lead: Lori Luchtman-Jones)
• Post-Thrombotic Sequelae (Lead: Ayesha Zia)
• VTE Risk Factors & Thromboprophylaxis (Lead: Vince Faustino)
• Arterial Thromboembolism (Lead: Mattia Rizzi)
• Duration of Anticoagulation (Lead: Hope Wilson)
• Early Career (Lead: Hilary Whitworth)
• Cardiac Thrombosis and Hemostasis (Lead: Amy L. Kiskaddon)

Task Force

• Cross-Network Data Harmonization and Data Sharing in Pediatric Thrombosis Research (Co-Leads: Julie Jaffray, Christine Sabapathy)

Projects

• International survey of vitamin K deficiency bleeding in infants, project began 2024; projected end: ongoing
• ECMO for pediatric pulmonary embolism – review of the ELSO database, project began 2024; projected end: ongoing
• Diagnosis and Treatment of Acquired Hemostatic Defects in Pediatric Liver Disease, project began 2024; projected end: ongoing
• Vitamin K deficiency bleeding in children with liver disease: a systematic review and meta-analysis, project began 2024; projected end: ongoing
• Prevalence of reproductive tract bleeding in adolescent females on anticoagulation and antiplatelet agents - A systematic review, project began 2024; projected end: ongoing
• Guidance for evaluation and reporting of medication adherence for clinical trials of
  anticoagulants in children, project began 2023; projected end: ongoing
• An International Cross-Sectional Assessment and SSC Communication on Pediatric Post-Thrombotic Sequelae Care, project began 2023; projected end: ongoing 
• Catheter associated NeoVTE (CA-NeoVTE) working party of Pediatric SSC, project began 2023; projected end: ongoing  
• International Pediatric Thrombosis Network: working together to advance the field of pediatric thrombosis
  project began: 2018; projected end: ongoing
• ISTH Database of DNA and Biorepository for Congenital Antithrombin Deficiency - a pilot/feasibility study
  project began: 2016; projected end: ongoing
• International Survey of the Management of Disseminated Intravascular Coagulation among Pediatric Health Care Practitioners
  project began: 2015; projected end: ongoing
• Homozygous protein C registry
  ongoing project

Official Communications:

• Minutes
• Bibliography
• Publication Guidelines