SSC Subcommittee on Pediatric and Neonatal Thrombosis and Hemostasis

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The Subcommittee is focused on addressing clinical and scientific issues in pediatric (including neonatal) thrombosis and hemostasis.

If you are interested in the subcommittee and want to follow its activity, please click "join community" to participate.


Mandate
  • To address issues in area of thrombosis in children and neonates.
  • To address issues in area of hemostasis in children and neonates.
  • To develop clinical standards for evaluation of children and neonates suffering from hemostasis and thrombosis problems.
  • To develop clinical research standards recommendations in children and neonates with hemostatic and thrombotic issues.
  • To develop international collaboration using registries, cooperative cohort studies, clinical trials or other appropriate methods in rare hemostasis and thrombosis problems in children and neonates.
  • To generate, publish and distribute reports and recommendations relating to pediatric and neonatal laboratory methods, standards and patient care.
  • To collaborate with other SSCs in appropriate situations.
  • To engage diverse, international, inter-disciplinary, inter-professional participation and representation at all stages of career, in all Pediatric/Neonatal SSC activities and initiatives.

Role

The following are the ongoing activities and responsibilities of the Subcommittee.

  • Educational Program: To continue to provide latest updates to all stakeholder communities (specialists, primary care providers, patients/parents, etc.) on diagnosis, treatment, outcomes, and prevention of disorders pediatric thrombosis and hemostasis, as well as latest recommendations, standards, guidelines/guidances, and research opportunities. 
  • Joint SSC Work: To continue to collaborate with other SSC chairs to promote crossover work, including for example physiologic inhibitors and thrombophilia, control of anticoagulation, and women’s health.
  • Position Papers: To continue to generate position papers to define current status in pediatric thrombosis & hemostasis and related research as well as to generate clinical guidance papers.
  • Working Parties: Groups of experts (hematologists and non-hematologists) have been assembled to further develop position papers relating to a variety of pediatric thrombosis & hemostasis issues.
  • Cooperative Registry and Cohort Study Initiation and Support: Promoting international collaboration to develop/maintain registries and cohort studies for rare pediatric thrombosis and hemostasis issues. Recent examples include the IPTN, AT registry, and severe PC registry.

If you are a member of the Society and would like to know how to participate in the work of this group, please join the group to receive updates on activity or submit an Expression of Interest Form to the Chairman or any of the Co-Chairmen. We would be pleased to learn of your interest.

Leadership

  • Chair - Madhvi Rajpurkar
  • Co-chair - Alessandra Bosch-Spiteri
  • Co-chair - Ernest Amankwah
  • Co-chair - Laura Avila
  • Co-chair - Sophie Jones
  • Co-chair - Christine Sabapathy 
  • Co-chair - Hale Ören
  • Co-chair - Lakshmi Srivaths
  • Co-chair - Hilary Whitworth 

Working Parties

Task Force

  • Cross-Network Data Harmonization and Data Sharing in Pediatric Thrombosis Research (Co-Leads: Julie Jaffray, Christine Sabapathy)

Projects

    Official Communications:

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    Announcements

    • Open for Public Comment: Development of new antithrombotic drugs for children (part 1)

      By: Erin Warren Erin Warren , 2 months ago

      Per the Guidelines and Guidance (G&G) Committee process for guidance manuscripts, draft manuscripts have to go through a public comment period and Committee review and approval before submitting the manuscript to the Journal of Thrombosis and Haemostasis (JTH).

      The G&G Committee would like to announce that the guidance manuscript titled, "Development of New Antithrombotic Drugs for Children (Part 1): Guidance from the ISTH SSC Subcommittee on Pediatric and Neonatal Thrombosis and Hemostasis and the Pedi-ATLAS Group," is now open for public comment. Note: This manuscript is confidential and in draft form.

      Please click here for a link to the guidance and to submit your comments by Thursday, October 30, 2025.

    • Invitation to Participate in Research Survey: SCOPE TXA

      By: Marie Sahin Marie Sahin , 3 months ago

      Dear Colleagues,

      You are invited to participate in a research survey titled "SCOPE TXA: Sickle Cell Observations of Provider Experiences with Tranexamic Acid." This study is being conducted by researchers at Central Michigan University and the Children's Hospital of Michigan. The purpose of this survey is to gather insights from providers across various specialties who care for patients with sickle cell disease. We are particularly interested in understanding the clinical scenarios in which tranexamic acid (TXA) has been used, how dosing is managed, and any considerations or hesitations providers may have regarding its use in this unique patient population.

      Even if you have not personally used TXA in patients with sickle cell disease, we are still very interested in your perspectives on the potential use of this medication in relevant clinical situations.

      Key details:

      · Estimated time to complete: 5–10 minutes

      · Confidentiality: Responses will remain confidential

      · Voluntary Participation: Participation is entirely voluntary and anonymous

      · IRB Approval: Central Michigan University IRB has approved this study

      · Compensation: Participants who complete the survey may choose to enter a drawing to win one of ten $50.00 gift cards. Gift cards will be delivered via mail.

      Your insights will help inform future clinical guidance and promote safe, evidence-informed care for individuals living with sickle cell disease.

      Please only complete the survey once, even if you receive it through multiple channels.

      https://redcap.cmich.edu/surveys/?s=7MFD9LP7FAKPXPAX

      If you have any questions, please do not hesitate to contact the principal investigator, Dr. Gianna Guzzardo Valenti, at Valen4g@cmich.edu or (313) 745-5515.

      Thank you for your time and valuable input. You can find more information about the study here:  SCOPE TXA_Research Information Sheet.docx

      Sincerely,

      Gianna Guzzardo Valenti, MD

      Children's Hospital of Michigan

    • The webinar on Health Literacy in Pediatric Thrombosis: A Landscape Analysis is scheduled for 03/3!

      By: Marie Sahin Marie Sahin , 11 months ago

      Date & Time: March 3 at 11 am EST/ 16 UTC

      In honor of blood clot awareness month, the ISTH, RPTH & World Thrombosis Day present a webinar on "Health Literacy in Pediatric Thrombosis: A Landscape Analysis." Hear from two of the study's authors, Laura Avila and Jennifer Vincelli. Mara Nuñez Toscano, WTD Steering Committee member, and Marisol Betensky, ISTH member, will moderate this insightful conversation.

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    Community Admins

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    Luke Blount
    ISTH
    Madhvi Rajpurkar image
    Madhvi Rajpurkar
    Children's Hospital of Michigan / Wayne State University/Central Michigan University
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