Dear Colleagues,
On behalf of the Hemostasis Working Party of the Pediatric/Neonatal Thrombosis and Haemostasis Subcommittee, we are pleased to invite your center to participate in a collaborative research initiative entitled “International Registry of Dengue Infection in Congenital Bleeding Disorders (DengueCBDR).” This study has been approved by the International Society on Thrombosis and Haemostasis.
Patients with congenital bleeding disorders are at increased risk of bleeding complications during dengue virus infection due to thrombocytopenia, platelet dysfunction, vascular leakage, and coagulopathy. Despite the clinical importance of this issue, there is currently a lack of comprehensive international registry data addressing bleeding manifestations, management strategies, and outcomes in this vulnerable population.
The primary objective of this study is to evaluate bleeding complications, management approaches, clinical outcomes, and associated complications in patients with congenital bleeding disorders—such as hemophilia, von Willebrand disease, and platelet disorders—who are affected by dengue infection. Your participation would make a valuable contribution to improving the understanding and management of bleeding in this clinical context.
To facilitate data collection, the study group has developed a REDCap-based electronic data capture system for patient registration. The full study proposal in English is available upon request for centers interested in participating.
Should you require further information or wish to express interest in joining this international registry, please contact Nongnuch.sir@mahidol.ac.th. or fill in your contact information https://docs.google.com/forms/d/e/1FAIpQLSdY8BM1O5nTQHJoSuW-Knm_EXBSaer5oh34JuuSNhLTqvrSUw/viewform?usp=header
We would be honored to collaborate with your institution on this important initiative.
Yours sincerely,
Nongnuch Sirachainan MD
On behalf of the Hemostasis Working Party
Pediatric/Neonatal Thrombosis and Haemostasis Subcommittee