SSC Subcommittee on Thrombosis and Antithrombotic Therapies

This subcommittee focuses on the laboratory and clinical use of antithrombotic drugs. It brings together internists, hematologists, cardiologists, and laboratory scientists to advance research and practice in the field.

Mandate

• To develop laboratory standards, methodologies, and nomenclature as needed.
• To facilitate international collaborations to design and conduct laboratory and clinical research.
• To organize and support collaborative studies that address identified needs.
• To address practical challenges faced by researchers and clinicians in antithrombotic therapies.
• To generate, publish, and disseminate reports, guidelines, and recommendations based on these activities.
• To facilitate discussions and foster critical review of the existing best evidence for related topics, to identify key areas of knowledge gap, and to promote collaborative original research in areas of high-priority knowledge gaps.

If you are a member of the Society and would like to know how to participate in the work of this group, please join the group to receive updates on activity or submit an Expression of Interest Form to the Chairman or any of the Co-Chairmen. We would be pleased to learn of your interest.

Leadership

• Chair - Lana Castellucci
• Co-chair - Rachel Rosovsky
• Co-chair - Jamilla Goedegebuur
• Co-chair - Nicolas Gendron
• Co-chair - Francois Mullier
• Co-chair - Behnood Bikdeli
• Co-chair - Isabelle Gouin-Thibault
• Co-chair - Sara Ng
• Co-chair - Tamrat Assefa Tadesse

Projects

• Extended secondary prevention of recurrent thrombotic events with lowdose direct oral anticoagulants in patients with splanchnic vein thrombosis
  project begins: 2024 projected end: 2027
• Identifying the global need for Anticoagulation Stewardship in perioperative anticoagulation management, project begins: 2025 projected end: 2026
• How to deal with interference on heparin anti-Xa activity caused by oral factor FXa inhibitors: communication from the ISTH SSC Subcommittee on Control of Anticoagulation project begins: 2025 projected end: completed
• Results of an international survey on the management of therapeutic-intensity unfractionated heparin: communication from the SSCs project begins: 2025 projected end: completed
• International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) – ISTH Working Group: Development of a Reference Measurement System for sustainable PT/INR standardization project begins: 2021 projected end: 2026
• Colchicine to Quench the Inflammatory Response after Deep Vein Thrombosis: The CONQUER-DVT pilot trial, project begins: 2024 projected end: 2026
• Impact of Pharmacist-Led Anticoagulation Service on Anticoagulation Outcomes, Knowledge, Adherence and Satisfaction among Ambulatory Patients Receiving Warfarin at Tikur Anbessa Specialized Hospital, Ethiopia: A Quasi-Experimental Study project began: 2022 projected end: 2023 - completing data analysis
• International Registry on the Diagnosis and Treatment of Inferior Vena Cava Thrombosis
  project began: 2020 projected end: 2023
• International registry on the use of the direct oral anticoagulants for the treatment of unusual site VTE
  project began: 2018 projected end: 2023 - completing follow-up, results will be submitted for publication soon
• Survey on anticoagulated patients – Register (START SSC - ISTH)
  registry is an ongoing project
• Antithrombotic Management of Cryptogenic Stroke in Patients with Cancer: A Survey of Physician Practices, project began: 2023 projected end: TBD - completing data analysis

Official Communications

• Minutes
• Bibliography
• Publication Guidelines