SSC Subcommittee on Perioperative and Critical Care Thrombosis and Hemostasis

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This subcommittee is focused on the perioperative management of anticoagulation, coagulopathy, and bleeding in patients who require surgery, procedural interventions, or in a critical care setting, and hemostatic management of critically ill patients requiring mechanical cardiopulmonary support.

If you are interested in the subcommittee and want to follow its activity, please click "join group" above to sign up as a member (follower).

Mandate

  • To promote research and knowledge regarding assessment and management of patients with inherited or acquired impairment of hemostasis in a perioperative and critical care setting.
  • To promote research and clinical applications of hemostatic management of critically ill patients requiring mechanical cardiopulmonary support including ventricular assist devices and extracorporeal membrane oxygenation.
  • To provide a vehicle for collaborative, multidisciplinary research in this field bringing together hematologists, cardiologists, internists, surgeons, intensivists, and anesthesiologists with interest in thrombosis and bleeding in the perioperative period, including the management of antithrombotics and hemostatic factors.

If you are a member of the Society and would like to know how to participate in the work of this group, please join the group to receive updates on activity or submit an Expression of Interest Form to the Chairman or any of the Co-Chairmen. We would be pleased to learn of your interest.

Our objective for the upcoming period is to continue our work focused on the perioperative management of anticoagulation, coagulopathy, and bleeding in patients who require surgery, procedural interventions, or in a critical care setting, and hemostatic management of critically ill patients requiring mechanical cardiopulmonary support. The intention is for our results to inform practice in these areas for our ISTH and global colleagues.

We will further strengthen ties with other SSC to collaborate on a variety of projects that are synergistic and combine the expertise of both committees to address a common problem. We are currently collaborating with the FXI and Contact System subcommittee. We will encourage our early career members to be involved with our SSC projects. We currently have 2 early career cochairmen. In addition, we want to expand our membership to include more Reach the World ISTH members and identify a reach the World Co-chair.

The main plans to achieve these goals are:

• PAUSE-2 pilot now funded by Canadian Grant
• Treatment of patients with acute HIT requiring cardiopulmonary bypass 
• Develop registry of plasma exchange treatment of patients with HIT prior to cardiopulmonary bypass

Leadership

  • Chair - Jean Connors  
  • Co-chair - Michael Mazzeffi
  • Co-chair - Nina Buchtele
  • Co-chair - Tina Tomic Mahecic
  • Co-chair - Deborah Siegal
  • Co-chair - Corinne Frere
  • Co-chair - Cheryl Maier
  • Co-chair - Joseph Shaw
  • Co-chair - Charles Marc Samama

Projects

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    Announcements

    • Open for Public Comment: Anticoagulation in HIT requiring Cardiac Surgery

      Per the Guidelines and Guidance (G&G) Committee process for guidance manuscripts, draft manuscripts go through a public comment period and G&G Committee review and approval before submitting the manuscript to the Journal of Thrombosis and Haemostasis (JTH).

       

      The G&G Committee would like to announce that the guidance manuscript titled, "Management of anticoagulation in patients with heparin-induced thrombocytopenia requiring cardiac surgery with cardiopulmonary bypass: Guidance from the ISTH SSC on Perioperative and Critical Care Haemostasis and Thrombosis," is now open for public comment. Note: This manuscript is confidential and in draft form.

       

      Please click here to submit your comments by Wednesday, November 12, 2025.

    • Public Comment Period Open: Guidance for Anticoag Pts Undergoing Surgery

      The ISTH would like to invite members to submit any comments for the draft guidance on the Surgical and Procedural Bleed Risk Stratification: Guidance for Anticoagulated Patients Undergoing Planned Surgery. 

      The manuscript is confidential and in draft form and should not be forwarded.

      Please click here to submit your comments by Monday, September 1, 2025.

      Kindly email Andrea Hickman at andrea_hickman@isth.org if you have any questions or concerns.

    • Identifying the global need for Stewardship in perioperative anticoagulation management

      Greetings: we are inviting clinicians to participate in an electronic survey on global perioperative anticoagulation management practices. The survey will take approximately 15 minutes to complete.

      It is hoped that any research output will benefit the standardisation of perioperative anticoagulation management and promote the uptake of Anticoagulation Stewardship internationally.

      You will not need to have experience with Antithrombotic Stewardship or Anticoagulation Stewardship to complete the survey.

      If you wish to participate in the survey or find out more information, please click here.

      We are also contactable anytime via email should you require any further information at: julianne.chong@health.nsw.gov.au.

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    Community Admins

    Brigham and Womens Hosp/Harvard Medical School
    United States